It is frequently found on the lower extremities, and it equally affects both sexes in the sixth and seventh decade. *Adenoid cystic carcinoma (ACC) facts written by Charles P. Davis, MD, PhD. adenoid cystic carcinoma pathology pathology in outline format with mouse over histology previews. It can also occur in the breast, uterus, or other locations in the body. It can also occur in the breast, uterus, or other locations in the body. It is also known as breast adenoid cystic carcinoma, abbreviated BACC. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. 62,278 Rare scattered cells show PSA and PAP immunoreactivity, but these may represent entrapped residual secretory luminal cells; other cells may show chromogranin staining. 5. In:Tumors of the salivary Glands.AFIP Atlas of Tumor pathology.Series 4.2008;pp 225-245. Human papillomavirus-related multiphenotypic sinonasal carcinoma, human papillomavirus-related carcinoma with adenoid cystic-like features, Intraductal carcinoma of the salivary gland, Adenoid cystic/basal cell carcinoma of the prostate, http://www.chestjournal.org/content/31/5/493.abstract, http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970070-5, https://librepathology.org/w/index.php?title=Adenoid_cystic_carcinoma&oldid=48982, Attribution-NonCommercial-ShareAlike 4.0 International, relatively common malignant salivary gland tumour. In our case, we present a 46- year-old female with a recurring exophytic tumor on the right lower extremity, without local extension. Pathology. Adenoid cystic carcinoma (AdCC) comprises of less than 1% of all head and neck cancers and less than 10% of all salivary gland neoplasms. INTRODUCTION. Primary cutaneous adenoid cystic carcinoma (PCACC) is a very rare malignancy. Adenoid Cystic Carcinoma: Stages Approved by the Cancer.Net Editorial Board , 08/2020 ON THIS PAGE: You will learn about how doctors describe an AdCC tumor’s growth or spread. Clin Otolaryngol Allied Sci. Pathology Outlines Adenoid cystic carcinoma (primary. Tumor cells show cribriform pattern of arrangement (H&E,X50) Twelve cases of pure adenoid cystic carcinoma of the breast were reviewed. Adenoid cystic carcinoma, abbreviated AdCC, is a malignant tumour commonly seen in the salivary gland. Contributed by Dr. Eman Abdelzaher, Alexandria University, Egypt. Adenoid cystic carcinoma. PCACC is part of a group of tumours called adenoid cystic carcinomas. ... Adenoid Cystic Carcinoma of Female Periurethral Area. If you do not want your question posted, please let us know. Three histologic patterns of ACC ha … Pathology of the Prostate - November 2017. Adenoid cystic carcinoma is a rare kind of cancer that usually starts in the glands that make saliva.These are under your tongue and on each side of your jaw below the jawbone. Do you have updated information on this disease? Adenoid cystic carcinomas are a rare histological subtype of adenocarcinoma. pathology outlines adenoid cystic carcinoma pathology outlines adenoid cystic carcinoma breast. May be angulated (carrot-shaped) - myoepithelial cells; round/ovoid in ductal cells. ; Suarez, C.; Rodrigo, JP. Adenoid Cystic Carcinoma Research Foundation. These resources provide more information about this condition or associated symptoms. Intermediate grade = solid component <30%. Dr Sampurna Roy MD ... Microcystic Adnexal Carcinoma a slow growing locally aggressive adnexal tumour was first reported by Goldstein et al, in 1982. This tumor most often occurs in the salivary glands, but it can also be found in many anatomic sites, including the breast, lacrimal gland, lung, brain, bartholin gland, trachea, and the paranasal sinuses. Moderate eosinophilic cytoplasm in the (rare) ductal cells. Adenoid cystic carcinoma is a rare type of cancer that can exist in many different body sites. Pathology Outlines Adenoid cystic carcinoma (primary. In the U.S., there are ∼15,000 patients with ACC alive today, and ACC thereby fulfills the criteria of the “rare (orphan) disease act” of 2002 (affecting <200,000 people in the U.S.). Compared with most other carcinomas, adenoid cystic carcinoma has a slow course with a survival rate of 89 percent at five years. We remove all identifying information when posting a question to protect your privacy. Get the latest research information from NIH: https://covid19.nih.gov (link is external). Adenoid cystic carcinoma (ACC) is a rare form of adenocarcinoma, a type of cancer that begins in glandular tissues.It most commonly arises in the major and minor salivary glands of the head and neck. Cystic spaces filled with basophilic material (that is PAS +ve) -. Gross pathology Adenoid cystic carcinoma of the parotid gland has deceptively well delineated outlines. Also, is this cancer genetic? Statistics adapted from the Adenoid Cystic Carcinoma Research Foundation, the National Organization for Rare Disorders, and the Oral Cancer Foundation (all accessed January 2020). Adenoid cystic carcinoma of the breast (upmc.edu). Submit a new question, We would like to know if this type of cancer can be environmental. (1996). In case of spread of cancer to other regions, chemotherapy may be considered by the healthcare provider. Common malignant neoplasm of salivary gland. His house was right in the landing path of the airplanes. Inclusion on this list is not an endorsement by GARD. ... Sarcomatoid Carcinoma of Male Urethra with Bone and Lung Metastases Presenting as Urethral Stricture. cribriform architecture (other patterns: solid, cords, (bilayered) tubules), cystic spaces filled with basophilic material, scant cytoplasm in most cells, nucleus - small, hyaline stroma. No. Tubular Carcinoma vs Cribriform Carcinoma. 5. 153 talking about this. (Feb 1986). Pathology Outlines (GA Tranesh); Photo: Dr. Mark Wick Beware of adenoid cystic carcinoma on the lower portion of the face! ADENOID CYSTIC CARCINOMA: A Comparative Pathologic Study of Tumors in Salivary Gland, Breast, Lung, and Cervix Jeffiy B. Lawrence, MD,* and Michael T. Mazur, MD'~ Histologic, histochemical, and ultrastructural features of eight adenoid cystic carcinomas arising at diverse sites were compared in order to determine diagnostic values and to investigate his- togenetic mechanisms. They consist of a mixture of proliferative glandular tissue (an adenoid component) and stromal or basement membrane elements (a pseudoglandular or cylindromatous component). Solid variant of mammary adenoid cystic carcinoma with basaloid features: a study of nine cases. You may want to review these resources with a medical professional. Adenoid cystic carcinoma: Tumor cells arranged in lobules separated by fibrous septa. Pathology outlines adenoid cystic carcinoma (primary. The neoplasm growth patterns are cribriform, tubular and solid and represent distinct differentiation stages. WebPathology is a free educational resource with 11065 high quality pathology images of benign and malignant neoplasms and related entities. •About 50% of cases are found in the subareolar region. Visit the group’s website or contact them to learn about the services they offer. Definition Adenoid cystic carcinoma is a slow growing and relentless salivary gland malignancy composed of epithelial and myoepithelial neoplastic cells that form various patterns, including tubular, cribriform , and solid forms. ; Futreal, PA.; Roberts, D.; Stephens, P.; Zhao, YJ. Have a question? Adenoid cystic carcinoma. pleomorphic adenoma, epithelial-myoepithelial carcinoma, intraductal carcinoma… Visual survey of surgical pathology with 11065 high-quality images of benign and malignant neoplasms & related entities. Abstract. Case Rep Urol. "Novel Chromosomal Rearrangements and breakpoints at the t(6;9) in Salivary Adenoid Cystic Carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome.". The in-depth resources contain medical and scientific language that may be hard to understand. Adenoid cystic carcinoma. ; Miettinen, M.; Wieneke, JA. Salivary gland tumors may cause painless masses in the mouth or face. HES1 is a well-known target gene of NOTCH signaling pathway. Microscopically, the tumor extends well beyond the grossly apparent edges of the tumor. Source: www.pathologyoutlines.com. Sometimes the planes were so low that you could actually see the people in the windows of the plane. ; Stelow, EB. We want to hear from you. Painful mass of the hard palate and maxillary alveolar ridge. Research helps us better understand diseases and can lead to advances in diagnosis and treatment. It most commonly arises in the major and minor salivary glands of the head and neck. Composed of ductal cells and myoepithelial cells; Other patterns: solid, cords, (bilayered) tubules. with transcription. Contrary to the head and neck region, benign SGT such as pleomorphic adenomas are exceedingly rare … This page was last edited on 9 May 2018, at 17:07. Cribriform type of salivary basal cell adenoma (cBCA) is relatively rare and problematic in distinction from adenoid cystic carcinoma (AdCC). Mitani, Y.; Rao, PH. One of the 'good prognosis' triple negative breast cancers - ER, PR and HER2 negative. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Adenoid cystic carcinoma. They can direct you to research, resources, and services. Pathology Outlines Adenoid cystic carcinoma (primary. Salivary gland tumors may cause painless masses in the mouth or face. Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Worse prognosis if present, esp. They account for only 0.1-0.4% of all breast cancers. Adenoid cystic carcinoma. Adenoid cystic pattern; Desmoplastic or myxoid stroma; Ki67 >20%; Strong diffuse bcl2 staining; Robert V Rouse MD Department of Pathology Stanford University School of Medicine Stanford CA 94305-5342 . The sinonasal tract is a common site of ACC occurrence, second only to the oral cavity. They share similar features under the microscope (see pathology of adenoid cystic carcinoma) but have distinct differences in clinical behaviour and prognosis. It explains what factors may increase the chance of developing AdCC. 5. 1986 Aug;11(4):267-91. ; Penner, C.; Ho, NJ. 2013;45(7):693–5. 31. ... Adenoid Cystic Carcinoma. The clusters contained admixed benign ductal cells and dense, metachromatic, magenta hyaline globular material with smooth, rounded outlines. Source: www.pathologyoutlines.com. Shin SJ, Rosen PP. Primary Adenoid Cystic Carcinoma of the Lung A Clinicopathologic and Immunohistochemical Study of 16 Cases Cesar A. Moran, M.D.,* Saul Suster, M.D.,t and Michael N. Koss, M.D. Microscopically, the tumor extends well beyond the grossly apparent edges of the tumor. Stell PM. Do you know of an organization? Adenoid Cystic Carcinoma. 1. Invasive breast carcinoma. Adenoid Cystic Carcinoma of Cervix . Adenoid cystic carcinoma •A carcinoma of low malignant potential, histologically similar to its counterpart in the salivary gland. See answer, If you have problems viewing PDF files, download the latest version of Adobe Reader, For language access assistance, contact the NCATS Public Information Officer, Genetic and Rare Diseases Information Center (GARD) - PO Box 8126, Gaithersburg, MD 20898-8126 - Toll-free: 1-888-205-2311, The underlying cause of adenoid cystic carcinoma (ACC) is not yet known, but it appears to develop from non-, Adenoid cystic carcinoma (ACC) is not considered to be an, expand submenu for Find Diseases By Category, expand submenu for Patients, Families and Friends, expand submenu for Healthcare Professionals. Adenoid cystic carcinoma (ACC) is the most common malignant tumor of the minor salivary glands. The usual presentation is with a unifocal, palpable, discrete, firm mass. We and our partners process personal data such as IP Address, Unique ID, browsing data for: Use precise geolocation data | Actively scan device characteristics for identification.. Tweets by @WebPathology. You can help advance Jena B. Hudson, Brian T. Collins, MYB Gene Abnormalities t(6;9) in Adenoid Cystic Carcinoma Fine-Needle Aspiration Biopsy Using Fluorescence In Situ Hybridization , Archives of Pathology & Laboratory Medicine, 10.5858/arpa.2012-0736-OA, 138, 3, (403-409), (2014). Original posting/last update: 6/1/12 Thompson, LD. Adenocystic carcinoma; Cribriform carcinoma; Cylindroma, placeholder for the horizontal scroll slider, Office of Rare Disease Research Facebook Page, Office of Rare Disease Research on Twitter, U.S. Department of Health & Human Services, Caring for Your Patient with a Rare Disease, Preguntas Más Frecuentes Sobre Enfermedades Raras, Como Encontrar un Especialista en su Enfermedad, Consejos Para una Condición no Diagnosticada, Consejos Para Obtener Ayuda Financiera Para Una Enfermedad, Preguntas Más Frecuentes Sobre los Trastornos Cromosómicos. "European results in neutron therapy of malignant salivary gland tumors.". •It could be salivary gland adenoid cystic carcinoma … (May 2009). Contact a GARD Information Specialist. Most patients are post-menopausal and white; the median age at diagnosis is between 50 and 63 years. Of all cases of sinonasal ACC, a minority (22 to 35%) arise in the nasal cavity. Or, you can choose another section to learn more about a specific question you have. ACC (Adenoid Cystic Carcinoma) is a rare and unique form of cancer that is known to be unpredictable in nature, with a typical growth pattern of being slow and gradual, but over time can be progressive, insidious and relentless. Adenoid cystic carcinoma (ACC) is a relatively rare form of cancer that most commonly develops in the salivary glands or other regions of the head and neck. Adenoid cystic carcinoma (ACC) is a relatively rare form of cancer that most commonly develops in the salivary glands or other regions of the head and neck. Adenoid cystic carcinoma (ACC) is a rare form of cancer (adenocarcinoma) that most often arises in the salivary glands but may occur in other locations like the breast or uterus. Sequeiros-Santiago, G.; García-Carracedo, D.; Fresno, MF. The most common tumors among this group are mucoepidermoid carcinoma and adenoid cystic carcinoma. ; Foss, RD. On pathologic analysis, it is characterized by the presence of mucin within the pseudocysts found in the tumor. Adenoid cystic carcinoma (ACC) is a rare form of adenocarcinoma, a type of cancer that begins in glandular tissues. Scant cytoplasm in most cells (myoepithelial cells) - clear/eosinophilic. Pathology outlines adenoid cystic carcinoma (primary cutaneous) Pathology Outlines Adenoid cystic carcinoma (primary cutaneous) Source: www.pathologyoutlines.com Adenoid Cystic CA : Microscopic. This study aims to evaluate the diagnostic accuracy of ACCA on fine needle aspiration (FNA) material and the associated challenges. Clinical: Adenoid cystic carcinoma (AdCC) of breast makes up less than 0.1% of all breast cancers. May 1957. Slide Index Neuropath Breast Head & Neck Mediastinum Peritoneum Adenoid cystic carcinoma (ACC) is an uncommon tumor primarily occurring in the salivary glands and is relatively rare in other sites. References ↑ Symptoms depend on the tumor 's location. Basal-like breast cancer - p63 and CK5/6 positive. The conjoined incidence of dysplasia, carcinoma in situ, and invasive carcinoma of the cornea and conjunctiva was estimated to … 2002 Apr;26(4):413-20. Adenoid Cystic CA : Microscopic. Our previous study demonstrated a close relationship between NOTCH signaling pathway and salivary adenoid cystic carcinoma (SACC). rare disease research! We want to hear from you. Results of S-100 protein and NSE stains are negative. The tumor demonstrates a strikingly characteristic microscopic pattern similar to that of adenoid cystic carcinoma of the salivary glands.. Squamous carcinoma of conjunctiva (cornea) Definition: malignant neoplasm of conjunctiva characterized by invasion of the substantia propria and squamous differentiation Incidence/Prevalence: squamous carcinoma is the most common conjunctival malignancy in adults. ; Symptoms and signs vary. Eccrine carcinoma is an extremely rare malignancy of the skin with few well documented cases reported in the literature. Differential Diagnosis. ; Moskaluk, CA. The trachea is a tubular structure of the respiratory system that … if fusion assoc. H&E stain. ; Gonzalez, MV. Pathology Outlines Adenoid cystic carcinoma (primary. Pathology of Microcystic Adnexal Carcinoma. This is Cancer.Net’s Guide to Adenoid Cystic Carcinoma. The tumors have a notable tendency for perineural spread. We want to hear from you. The differential diagnoses include neoplasms composed of either basaloid cells and/or admixed hyaline matrix material and included pleomorphic adenoma, basal cell adenoma and adenoid cystic carcinoma. Objectives. http://www.cancer.net/cancer-types/adenoid-cystic-carcinoma/overview, http://www.oralcancerfoundation.org/facts/rare/ac/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077968/, https://www.accrf.org/living-with-acc/understanding-acc/, http://www.sciencedirect.com/science/article/pii/S2212555814000477, https://www.ncbi.nlm.nih.gov/pubmed/28210977. Symptoms depend on the tumor 's location. Chest. H&E stain. LM DDx. Use the menu below to choose the Introduction section to get started. "Primary adenoid cystic carcinoma of the skin. Pathology. Adenoid cystic carcinoma (ACC) is an uncommon form of malignant neoplasm that arises within secretory glands, most commonly the major and minor salivary glands of the head and neck. Solid Variant of Mammary Adenoid Cystic Carcinoma With Basaloid Features: A Study of Nine Cases Mammary-type Myofibroblastoma: Clinicopathologic Characterization in a Series of 143 Cases Histologic Grading of Prostatic Adenocarcinoma Can Be Further Optimized: Analysis of the Relative Prognostic Strength of Individual Architectural Patterns in 1275 Patients From the Canary Retrospective Cohort AdCC of breast - solid type (WC/Sarahkayb). Surgically resected salivary gland tumors diagnosed as AdCC (n = 219) in 15 reference hospitals in Japan were subjected to a retrospective pathological re‐evaluation. Am J Surg Pathol. Adenoid cystic carcinoma. ; Zhang, L.; Mitani, M. et al. White or grayish white color, firm, invasive tumor. The cribriform pattern displays pseudo‐cystic structures, formed by neoplastic cells of either myoepithelial or epithelial phenotype ( Seifert & Sobin 1992 ). Adenoid cystic carcinoma has also been reported in the breast, lacrimal gland of the eye, lung, brain, bartholin gland, and trachea. CD117 positive. Urology. Other sites of origin include the trachea, lacrimal gland, breast, skin, and vulva. Patients ranged in age from 34 to 69 years. Gross pathology Adenoid cystic carcinoma of the parotid gland has deceptively well delineated outlines. Adenoid cystic carcinoma of the breast is a rare type of breast cancer that is similar to a relatively common tumour of the salivary gland . C. The cystic spaces contain mucoid or hyalinized material D. The primary site of laryngeal adenoid cystic carcinoma is the vocal cords themselves... E. This tumor is clinically aggressive, reflected by the high mitotic rate and basaloid cells https://www.pathologyoutlines.com/topic/larynxacc.html… # pathology # pathologyoutlines # imagequiz # larynx # carcinoma Here we presented a primary hepatic adenoid cystic carcinoma in a 44 years old male. PP. Adenoid Cystic Carcinoma • Gross Pathology: • - uncapsulated firm solid tan mass • Histology: highly infiltrative small hyperchromatic cells cribriform (“Swiss cheese”), tubular, solid mucohyaline stroma Perineural invasion 69 70. (Oct 2011). This tumour shows both eccrine and pilar differentiation. The next section in this guide is Risk Factors. Myoepithelial markers (e.g. * Background. White or grayish white color, firm, invasive tumor. painless masses in the mouth or face, bulging eye or vision change, "Sinonasal Tract and Nasopharyngeal Adenoid Cystic Carcinoma: A Clinicopathologic and Immunophenotypic Study of 86 Cases.". Pathology Adenoid cystic carcinomas are generally considered low grade 4. calponin, actin) +ve. ACC can occur in other parts of the body, such as the breast, skin, cervix in females, prostate gland in males, and various other areas. Pulmonary salivary gland-type tumors (SGT) comprise a very small proportion of primary lung neoplasms. The purpose of the present study was to further explore the molecular mechanism of HES1 in SACC. Adenoid Cystic Carcinoma of Trachea is known to metastasize to the local lymph nodes and lungs. Conversely, adenoid cystic carcinoma of the breast is a rare type of triple-negative (estrogen and progesterone receptor, HER2) and basal-like carcinoma, which in contrast to other triple-negative and basal-like breast carcinomas has a very favorable prognosis. Some partners do not ask for your consent to process your data, instead, they rely on their legitimate business interest. Epidemiology. Vol. Throat Cancer Hpv Cystic Carcinoma Outlines Adenoid Pathology beltone vs Miracle Ear Nonin Ear Clip Sensor 3 foot cable in 1982, making it uncertain vital areas – the eyes; Rapidly shifting back in place tubes in code 92502 (otolaryngologic examination 0. Questions sent to GARD may be posted here if the information could be helpful to others. Adenoid cystic carcinoma (ACCA) is an uncommon primary malignancy of salivary glands and rarely nonsalivary tissue. Thank you for joining our Facebook page. Adenoid cystic carcinoma 1. Bhardwaj M, Gupta P. Dedifferentiated adenoid cystic carcinoma ex pleomorphic adenoma of the parotid. This section provides resources to help you learn about medical research and ways to get involved. Low grade cribriform carcinoma and tubular carcinoma both have nearly 100% survival; We report mixtures of these two types simply as the predominant type SGH Pathology Adenoid cystic carcinoma (ACC) is, despite its deceptively low‐grade histological appearance, an aggressive type of salivary gland malignancy arising in major and minor salivary glands. (Sep 2013). IHC. Adenoid cystic carcinoma of the breast displays slowly progressive growth and rarely metastasizes to the axillary lymph nodes. "Oncogene amplification pattern in adenoid cystic carcinoma of the salivary glands.". Pathology Outlines . Adenoid cystic carcinoma (ACC) is a rare but distinctive salivary gland-type malignant neo- plasm that arises infrequently as a primary tumor in the lung. pathology outlines adenoid cystic carcinoma pathology outlines adenoid cystic carcinoma breast. Adenoid Cystic CA : Intro & Clinical. LM. Background. This tumor most often occurs in the salivary glands, but it can also be found in many anatomic sites, including the breast, lacrimal gland, lung, brain, bartholin gland, trachea, and the paranasal sinuses.. Pathology outlines adenoid cystic carcinoma (primary. Adenoid cystic carcinoma/basal cell carcinoma displays variable immunoreactivity with keratin 34βE12; luminal cell staining or peripheral basal cell staining may occur. The treatment of choice is a surgical excision with clear margins followed by radiation therapy. Article Google Scholar 14. They may cause. surgpathcriteria.stanford.edu/breast/adcystcabr/printable.html 493-511. Types of adenoid cystic carcinoma include: Cutaneous (described here) Salivary (most common) Other Resources. To assess the role of a central pathology review in the diagnosis of salivary gland adenoid cystic carcinoma (AdCC). Adenoid Cystic Carcinoma (ACC) of Trachea is a very rare and unusual form of cancer. My father in law worked at an automotive company for over 30 years and he also lived very close to the airport. ACC can occur in other parts of the body, such as the breast, skin, cervix in females, prostate gland in males, and various other areas. PMID: 3028679 [PubMed - indexed for MEDLINE] Publication Types: Screening Programme’s Guidelines for Pathology Reporting in Breast Cancer Screening and the Second . Methods. Adenoid cystic carcinoma (ACC) is a frequent malignant salivary gland neoplasm. A. Immunohistochemical staining for CD117 will be negative in tumor cells B. Perineural invasion is extremely rare in this type of tumor C. The cystic spaces contain mucoid or hyalinized material D. ... Adenoid Cystic Carcinoma of Cervix. Do you know of a review article? Adenoid cystic carcinoma 2. Adenoid cystic carcinoma of the breast. The differential diagnosis of PCACCs in pathology practice can be difficult and a group of primary and metastatic lesions, including adenoid basal cell carcinoma of the skin, should be considered in the differential diagnosis. Get the latest public health information from CDC: https://www.coronavirus.gov (link is external) Trendell-Smith NJ, Peston D, Shousha S. Adenoid cystic carcinoma of the breast: a tumour commonly devoid of oestrogen receptors and related proteins. Low grade = tubules and cribriform structures only; no solid component. A clinical, histological, and immunocytochemical comparison with adenoid cystic carcinoma of salivary glands and adenoid basal cell carcinoma.". In the liver, only one primary adenoid cystic carcinoma has been reported in the English literature. Comparative transcriptome analyses by RNA-Sequencing (RNA-Seq) were employed to reveal … Light and Electron Microscopic Study. Adenoid cystic carcinoma is a rare type of cancer that can exist in many different body sites. See also. •Comprising < 0.1% of breast carcinomas. Painful mass of the hard palate and maxillary alveolar ridge. adenoid cystic carcinoma pathology pathology in outline format with mouse over histology previews. Adenoid cystic carcinoma of the breast (ACC) is an extremely rare tumor accounting for <0.1% of all breast cancers diagnosed [1– 3].It is known to have a dual cell population of both luminal and basal cells making it indistinguishable from ACC arising in salivary tissue [1– 3].Most commonly the tumors present as well circumscribed, painful, palpable masses [2– 4]. Wick, MR.; Swanson, PE. Krüll, A.; Schwarz, R.; Engenhart, R.; Huber, P.; Lessel, A.; Koppe, H.; Favre, A.; Breteau, N. et al. Image quiz: Which of the following is true about this adenoid cystic carcinoma of the larynx?